Cardiac MRI Radiomics Predicts Reverse Remodeling in Dilated Cardiomyopathy

Radiomic scores from cardiac MRI T1 and ECV maps had an AUC of 0.834 and 0.718, respectively, for predicting left ventricular reverse remodeling in dilated cardiomyopathy, improving AUC of late gadolinium enhancement from 0.618 to 0.903 when combined.

• Among 74 patients with nonischemic dilated cardiomyopathy, 42% (31/74) achieved LVRR after optimized medical therapy.
• Patients with LVRR had higher T1-RadScore (0.72±1.52 vs -1.54±2.66; P<0.0001) and lower late gadolinium enhancement extent (0.19±0.58 vs 2.99±6.5; P=0.047).
• The combined model (radiomic scores + late gadolinium enhancement) achieved an AUC of 0.903, significantly higher than late gadolinium enhancement alone (0.618; P<0.0001).

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