Functional CAD-RADS (CT-FFR) Boosts 5-Year MACE Prediction Over Anatomical CAD-RADS in Stable CAD

Functional CAD-RADS predicts MACE better than anatomical CAD-RADS (C-index 0.780 vs 0.723; p=0.035) with fewer inappropriate management decisions (9.9% vs 11.0%).

• Inappropriate management decisions per functional CAD-RADS had a MACE HR of 9.544 (95% CI 5.794–15.720), versus HR 2.475 (95% CI 1.369–4.474) for anatomical CAD-RADS.

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