Higher Thrombectomy Volumes Associated with Lower Mortality in Acute Stroke

Every 10-case increase in mechanical thrombectomy volume for acute ischemic stroke was associated with a 1.2% reduction in odds of mortality (OR 0.988, 95% CI 0.980–0.995, p=0.001). However, cardiac and pulmonary complications remain common, affecting 40.5% and 30.5% of patients.

• The study analyzed 27,797 cases from the National Inpatient Sample (2017–2021), with case volumes rising annually.
• Despite expanded time windows for thrombectomy, the volume-outcome relationship persisted, with lower mortality at higher-volume centers.
• High complication rates (71.7% overall) highlight an opportunity to improve outcomes, especially at lower-volume institutions.

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