GRASP DCE-MRI Detects Treatment Response After Radiosurgery for Head and Neck Paragangliomas

GRASP DCE-MRI detected significant post-radiosurgery reductions in wash-in slope, wash-out slope, and peak enhancement (p≤.02) in head & neck paragangliomas, suggesting it may serve as a treatment response biomarker.

• Retrospective study of 14 patients with head and neck paragangliomas imaged before and a median of 26 months after gamma-knife SRS.
• Tumor volume decreased modestly (median change −0.18 mL, p=.001) or remained stable in all but one case.

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