French Guidelines on NMOSD: MRI Features and Urgent Attack Management

French guidelines for NMOSD: MRI reveals extensive optic nerve (posterior) and central cord lesions. Diagnose with serum anti-AQP4 antibodies. Treat acute attacks urgently with IV corticosteroids/plasma exchange—don't wait for antibody results.

• Area postrema syndrome presents with nausea, vomiting, and intractable hiccups, often requiring hospitalization.
• First-line maintenance therapy includes monoclonal antibodies (anti-B lymphocyte, anti-IL6 receptor, anti-complement C5); conventional agents like azathioprine are less common first-line but remain possible.
• Pregnancy is high-risk with increased relapse risk postpartum; multidisciplinary follow-up including ophthalmology and neuropsychology is essential.

Automated summary

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