Gastric Cancer T4a vs T4b Differentiation Using Multiscale CT Fusion Model

A multiscale fusion model (GAVR) achieved AUC 0.987 in prospective validation for differentiating T4a from T4b gastric cancer on CT. It boosted radiologists' accuracy from 0.609 to 0.795 and cut reading time 60% in a reader study.

• In external validation sets, AUCs were 0.987 and 0.979; prospective validation AUC was 0.987, across 1804 patients.
• Ablation studies confirmed the necessity of multiscale spatial features for the model's performance.
• GAVR assistance improved 16 radiologists' accuracy from 0.609 to 0.795 and reduced reading time by 60%.

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