Radiomic Model with SHAP Predicts pGGN Invasiveness

A combined radiomic-clinical model predicted invasiveness of pure ground-glass nodules (pGGNs) with an AUC of 0.832 in the test set, outperforming a clinical model (AUC 0.733). SHAP analysis identified the most important radiomic feature.

• The study included 235 surgically resected pure ground-glass nodules.
• The combined model integrated two CT features (mean CT value, VolumePercent₋₃₀₀) and eight radiomic features.

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