Age-specific norms for main pulmonary artery-to-ascending aorta ratio on pediatric chest CT

In a multicenter study of 1306 children, age-adjusted MPA/AA ratio on chest CT predicted invasive pulmonary arterial pressure elevation with an AUC of 0.881 (95% CI 0.830-0.932). The ratio declines with growth, so age-specific norms are needed.

• The median MPA/AA ratio was 1.12; the ratio was highest in early life, declined with growth, and stabilized later.
• In an independent right heart catheterization cohort of 169 children >3 months, the age-adjusted ratio detected pressure elevation with AUC 0.881.

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