Super-resolution MRI reconstruction does not improve radiomics prediction of placenta accreta spectrum

In a multicenter study of 603 patients, a radiomics model using super-resolution T2-weighted MRI did not outperform standard-resolution images for predicting placenta accreta spectrum disorders. The 4× model achieved an AUC of 0.874 in training, but no statistically significant…

• In external validation across two centers (n=66 and n=57), radiomics model AUCs ranged from 0.542 to 0.724, indicating only moderate generalizability.
• DeLong tests showed no statistically significant differences in AUC among 1×, 2×, and 4× super-resolution models for any classifier (all P > 0.05).
• The authors concluded that diagnostic information relevant to placenta accreta spectrum may be adequately captured at original resolution and do not recommend routine super-resolution reconstruction for this application.

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