AJR Expert Panel Consensus on Imaging After Negative PSMA PET/CT in Prostate Cancer Biochemical Recurrence

In prostate cancer biochemical recurrence, guidelines say salvage radiation shouldn't be withheld despite negative PSMA PET/CT. Yet imaging is often pursued. AJR Expert Panel consensus: use PSA kinetics and tumor biology to select further imaging, such as repeat PSMA PET/CT or a…

• Existing guidelines recommend not withholding salvage radiation therapy based on a negative PSMA PET/CT result.
• Consensus statements emphasize PSA kinetics and tumor biology to guide selection of repeat PSMA PET/CT, alternative radiotracers, or other modalities.
• The review identifies areas requiring additional data to support informed clinical decision-making.

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