AI whole-prostate volumetry matches ellipsoid formula for PSA density risk stratification

AI-derived prostate volume for PSA density (PSAD) calculation is non-inferior to the manual ellipsoid formula for detecting clinically significant prostate cancer (csPCa). AI-PSAD achieved an AUC of 0.79, while manual-PSAD ranged from 0.76 to 0.78 (one reader’s AUC was significa…

• In 171 patients undergoing MRI/transperineal fusion biopsy, both AI- and ellipsoid-formula-derived PSAD correlated significantly with ISUP grade group (all p<0.001).
• This was a single-centre retrospective study using a single commercial AI tool on 3-T MRI datasets, so generalizability may be limited.

Automated summary

RadPigeon summaries are original and for information only. They are not clinical advice.