Nuclear / MolecularNews

Second PSMA PET alters management in nearly half of prostate cancer patients after negative first scan

Radiology BusinessJul 13

Repeat PSMA PET after an initially negative scan detected disease in ~56% of recurrent prostate cancer patients and changed management in nearly 50%, per a new study in JNM.

  • The study analyzed 210 patients from the Ontario PSMA PET Registry who had a negative first scan; the second PET found disease in about 56%.
  • Positive repeat scans were more likely in patients with higher PSA levels and a PSA doubling time under 12 months.
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