Prompt Complexity Does Not Impact AI Accuracy in Organic Chemistry Education

AI systems ChatGPT 5 and GPT IQQO showed similar conceptual adequacy (92.8% vs 93.1%) in organic chemistry tasks, regardless of prompt complexity. User competence matters more than architecture. Orbital interactions was the weakest category (88% adequacy).

• Content analysis of 494 coded segments from two AI systems responding to organic chemistry prompts (Cannizzaro reaction, guanidine group).
• Performance was comparable across prompt complexity levels; the most vulnerable conceptual area was orbital interactions (88.0% adequacy).
• Limitation: Single-domain study in organic chemistry, not validated in radiology or medical education contexts.

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