YOLOv8 Model for Knee X-ray Abnormality Detection Shows Strong Localization but Moderate Diagnostic Accuracy

In a retrospective study of 3,200 patients, DeepKneeXR localized knees with mAP 0.995 but provided only moderate probabilities for meniscal tears, MCL injuries, and joint effusion on AP radiographs; external validation needed.

• Retrospective single-center proof-of-concept; 3,200 adults, composite reference standard (exam, MRI, arthroscopy).
• Multi-label abnormality detection was moderate, with limited validation AUC for joint effusion (exact figures not reported).
• Single-center retrospective design without external validation limits generalizability.

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