Semiautomated MRI breast density from routine sequences correlates well with mammography but yields lower values

MRI-based breast density from routine T1 sequences correlated strongly with mammographic density (r=0.781) but was on average 27.7% lower in a study of 113 women. AUC for high-density detection was 0.869 for MRI vs 0.799 for mammography (P=0.085).

• Single-center retrospective study in 113 women (mean age 61) with both MRI and mammography, analyzing contralateral normal breast.
• MRI density strongly correlated with mammographic density (r=0.781, p<0.001) but MRI values were 27.7% lower.
• AUC for detecting high-density breasts was 0.869 (MRI) vs 0.799 (mammography); difference not statistically significant (p=0.085).

Single-center retrospective design; deep learning segmentation required manual correction; no external validation; difference in AUC not statistically significant.

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