MRI Pulse Sequences: Spoiled GRE vs. SSFP-FID (FISP) Key Differences Explained

Spoiled gradient echo (GRE, e.g., FLASH) destroys residual transverse magnetization with spoiler gradients or RF spoiling, producing T1-weighted contrast. Steady-state free precession (SSFP-FID, known commercially as FISP) rephases it, yielding mixed T2*/T1 contrast and bright f…

• Explains the physics of spoiled GRE and SSFP-FID sequences, including the role of spoiling and rephasing.
• Discusses commercial names (e.g., FLASH, SPGR for spoiled; FISP for SSFP-FID) and typical contrast characteristics.
• Intended as a learning resource for radiology residents and MR technologists.

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