Portuguese consensus on renal denervation for uncontrolled hypertension

Portuguese consensus: Renal denervation with radiofrequency or ultrasound may be considered for uncontrolled hypertension despite optimal therapy, based on sham-controlled trials showing sustained BP reductions and a favorable safety profile. Rigorous patient selection within mu…

• Evidence synthesis: Sham-controlled trials and real-world registries demonstrate sustained blood pressure reductions with both radiofrequency and ultrasound systems (exact figures not reported in source).
• Limitation: Long-term clinical outcomes and individual response prediction remain uncertain.
• Organizational requirements: Centers must have structured pathways, pre-procedural imaging, peri-procedural management, and standardized follow-up with ambulatory monitoring.

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