Using DWI-FLAIR Mismatch to Select Wake-Up Stroke Patients for Aggressive Treatment

DWI-positive/FLAIR-negative mismatch on MRI suggests wake-up stroke symptom onset within 4–6 hours, potentially indicating eligibility for aggressive therapy.

• Educational short video from LearnNeuroradiology demonstrates assessment of the DWI-FLAIR mismatch sign.
• Teaches that restricted diffusion with normal FLAIR implies a stroke likely within the time window for thrombolysis or thrombectomy.
• Aimed at radiologists and trainees interpreting emergency stroke imaging; no original study data.

RadPigeon summaries are original and for information only. They are not clinical advice.