Cardiac MRI parameters fill a prognostic gap in heart failure risk prediction

In a large prospective cohort, adding native T1 and extracellular volume to clinical models improved heart failure risk prediction (AUC 0.82 vs 0.76, p<0.001), reclassifying 1 in 5 patients.

• Prospective observational study (n=3,200; community-based adults without baseline heart failure); analysis performed with internal validation.
• Key secondary finding: Native T1 >1,050 ms independently predicted incident heart failure (HR 2.1 [95% CI 1.6–2.7]).
• Limitation: Single-country cohort; external validation in diverse populations is not yet done.

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