RFA for adrenal adenomas: aldosterone- vs cortisol-producing lesions compared

Comprehensive review contrasts radiofrequency ablation outcomes for aldosterone-producing vs cortisol-producing adrenal adenomas. RFA is better characterized for APA; CPA data remain sparse. Key clinical, imaging, and procedural differences are detailed for interventional radiol…

• Narrative review in JVIR synthesizing published literature on RFA for functioning benign adrenal adenomas in patients unfit for adrenalectomy; exact pooled n not reported in source.
• Aldosterone-producing adenomas (APA) are treated far more frequently with RFA than cortisol-producing adenomas (CPA), so outcomes data are more robust for APA; reasons for this disparity — including pathological and hormonal differences — are a central focus.
• Key limitation: review design with inherent selection and publication bias; quantitative outcomes (technical success rates, biochemical cure rates with CIs) not extractable from the available abstract.

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